Η έρευνα που διενεργείται στο ΙΕΛΥΑ στο αντικείμενο των Ασθενειών προσαρμόζεται στις σύγχρονες απαιτήσεις της γεωργίας και στοχεύει στην αντιμετώπιση των φυτονόσων θέτοντας ως απαραίτητη προϋπόθεση την υγεία του καταναλωτή και την προστασία του περιβάλλοντος. Πεδία έρευνας αποτελούν:
- η μελέτη ενδημικών και νέων-αναδυόμενων ασθενειών σε σημαντικές καλλιέργειες (π.χ. αμπέλι, ελιά, εσπεριδοειδή,υποτροπικά, κηπευτικά).
- η ανάπτυξη καινοτόμων διαγνωστικών μεθόδων με τη συνδυαστική χρήση διεπιστημονικών τεχνολογιών.
- η μελέτη της πληθυσμιακής δομής, των στοιχείων βιολογίας, φυσιολογίας, γενετικής και επιδημιολογίας των υπαίτιων παθογόνων.
- η διερεύνηση της αλληλεπίδρασης φυτοπαθογόνων μικροβίων με τα φυτά-ξενιστές και το περιβάλλον και η κατανόηση των μηχανισμών παθογένεσης και άμυνας, συμβάλλοντας στη χάραξη καινοτόμων στρατηγικών ολοκληρωμένης διαχείρισης ασθενειών.
Σε πρακτικό επίπεδο, πραγματοποιείται αξιολόγηση των μεθόδων διαχείρισης ασθενειών που αφορούν στην αξιοποίηση ανθεκτικών γονοτύπων φυτών, βιολογικών παραγόντων, αλλά και στη βελτιστοποίηση ήδη υπαρχόντων μέσων διαμέσου διαχείρισης της ανθεκτικότητας των φυτοπαθογόνων στα χημικά σκευάσματα.
Με τις Ασθένειες ασχολούνται οι Δρ. Μαρκάκης, Δρ. Μαθιουδάκης, Δρ. Παππή, Δρ. Καβρουλάκης.
Mathioudakis M.M., Varikou K., Karagianni A, Psirofonia P, Tektonidis N, Kapantaidaki D, Evangelou V, Economou L, Hasiów-Jaroszewska B, Potamitis I. 2025 Aphid Species in Citrus Orchards in Crete: Key Vectors of Citrus Tristeza Virus and Automated Monitoring Innovations for Alate Aphid Viruses, 17, 395.
Tzanetakis IE, Aknadibossian V, Špak J, Constable F, Harper SJ, Hammond J, Candresse T, Folimonova SY, Freitas-Astúa J, Fuchs M, Jelkmann W, Maliogka VI, Marais A, Martin RR, Mollov D, Vidalakis G, Aboughanem-Sabanadzovic N, Al Rwahnih M, Alabi OJ, Alioto D, Atanda HY, Bagi F, Baranwal VK, Barbosa C, Bar-Joseph M, Batista Le Riverend L, Belien T, Benítez-Galeano MJ, Bennypaul H, Bertaccini A, Bester R, Blouin AG, Blystad DR, Botermans M, Bozan O, Brakta A, Brans Y, Bulajić A, Caglayan K, Catara A, Choueiri E, Cieślińska M, Cook G, Cui W, da Graça J, Davino S, Delmiglio C, Dewdney MM, Di Serio F, Diaz-Lara A, Digiaro M, Djelouah K, Dong YF, Donovan N, Druciarek TZ, Duran-Vila N, Elçi E, Esquivel-Fariña A, Fall ML, Fan XD, Figueroa J, Fiore N, Fowkes AR, Fox A, Fránová J, Fuchs R, Gaafar YZA, García ML, Ghosh D, Girardi E, Glasa M, Gomez Talquenca S, Gratz A, Gritsenko D, Hajeri S, Hajizadeh M, Hamborg Z, Ho T, Holeva M, Holkar SK, Horner M, Hurtado-Gonzales OP, Ippolito A, Isac V, Iwanami T, Jofre-Y-Garfias AE, Jordan R, Katis N, Koloniuk I, Konings H, Križanac I, Krueger R, Kyrychenko A, Laranjeira F, Lavagi-Craddock I, Levy A, Licciardello G, Lu QY, MacFarlane SA, Marcone C, Maree HJ, Margaria P, Martić A, Massart S, Mathioudakis M.M., Matić S, Mavric Plesko I, Meekes ETM, Mehle N, Melzer MJ, Meng B, Menzel W, Miljanić V, Minafra A, Minutolo M, Mitra A, Moreno P, Navarro L, Navarro B, Nerva L, Okić A, Olmos A, Önelge N, Osundahunsi B, Palacios MF, Pallas V, Panno S, Perez-Egusquiza Z, Poudel-Ward B, Radišek S, Ramos-González PL, Ramteke P, Ranabhat NB, Rivarez MPS, Rivas F, Roenhorst A, Roy A, Ruiz-García AB, Sabanadzovic S, Šafářová D, Saldarelli P, Salem N, Sanahuja Solsona G, Schoen R, Sharma SK, Shilts T, Sierra-Mejia A, Singh S, Skelton A, Škorić D, Stainton D, Štajner N, Starović M, Stuchi E, Svoboda P, Tahzima R, Tang J, Tessitori M, Thermoz JP, Thompson E, Thompson J, Trebicki P, Turina M, Ulubas Serce C, Umble J, Valiunas D, Varallyay E, Varma A, Varveri C, Vásquez-Gutiérrez U, Vazquez-Iglesias I, Veerakone S, Villamor DE, Vives MC, Vončina D, Wang J, Westenberg M, Wetzel T, Winter S, Wright G, Wulff NA, Xu WX, Yokomi R, Zhou C, Zikeli K, Zindović J. 2025 Streamlining Global Germplasm Exchange: Integrating Scientific Rigor and Common Sense to Exclude Phantom Agents from Regulation Plant Disease , 109, 736-755.
Argyriou, A.V.; Tektonidis, N.; Alevizos, E.; Ferentinos, K.P.; Kourgialas, N.N.; Mathioudakis, M.M. 2024 Precision Farming Multimodal Technologies Using Optical Sensors for the Detection of Citrus Tristeza Virus Endemics Sustainability , 16, 5748.
Mathioudakis, M.M, Tektonidis, N., Karagianni, A., Mikalef, L., Gómez, P., Hasiów-Jaroszewska, B. 2023 Incidence and Epidemiology of Citrus Viroids in Greece: Role of Host and Cultivar in Epidemiological Characteristics Viruses, 15, 605.
Katsiani, A., Panailidou, P., Mathioudakis, M.M., Katis, N., Maliogka, V.I. 2022 Identification and complete genome sequencing of a divergent olive virus T isolate and an olive leaf yellowing-associated virus isolate naturally infecting olive trees in Greece Virus Genes, 58, 560-569.
Dhir, S., Mathioudakis, M.M., Hasiów-Jaroszewska, B., Hallan, V. 2021 Serological and molecular analysis indicates the presence of distinct viral genotypes of apple stem pitting virus in India. 3 Biotech, 11, 278.
Mathioudakis, M.M., Maliogka, V.I., Candresse, T., Nickel, O., Fajardo, T.V.M., Budzyńska, D., Hasiów-Jaroszewska, B., Katis, N.I. 2021 Molecular Characterization of the Coat Protein Gene of Greek Apple Stem Pitting Virus Isolates: Evolution through Deletions, Insertions, and Recombination Events. Plants , 10, 917.
Katsarou, K., Chiumenti, M., Kalantidis, K., Mathioudakis, M.M. 2020 First report of citrus viroids infecting Persian (Tahiti) lime in Greece. Plant Disease , 104, 998.
Mathioudakis, M.M., Saponari, M., Hasiow-Jaroszewska B., Elbeaino, T., Koubouris, G. 2020 Detection of viruses in olive cultivars in Greece, using a rapid and effective RNA extraction method, for certification of virus-tested propagation material. Phytopathologia Mediterranea , 59, 137-146.
Mathioudakis, M.M., Stournaras, V., Elbeaino, T. 2020 First report of fig leaf mottle-associated virus 1 infecting common fig in Greece. Plant Disease , 104, 2534.
Mathioudakis, M.M., Tziros, G., Kavroulakis, N. 2020 First report of Diaporthe foeniculina associated with avocado branch canker disease in Greece. Plant Disease , 104, 3057.
Orfanidou, C.G., Mathioudakis, M.M., Katsarou, K. Livieratos, I., Katis, N.I., Maliogka, V.I. 2019 Cucurbit chlorotic yellows virus p22 is a suppressor of local RNA silencing. Archives of Virology, 164, 2747-2759.
Papoutsis K., Mathioudakis M.M., Hasperue J.H. and Ziogas V. 2019 Non-chemical treatment for preventing the prostharvest fungal rotting of citrus caused by Penicillium digitatum (green mold) and Penicilium italicum (blue mold) Trends in Food Science & Technology , 86, 479-491.
Mathioudakis, M.M., Khechmar, S., Owen, C.A., Medina, V., Ben Mansour, K., Tomaszewska, W., Spanos, T., Sarris, P.F., Livieratos, I.C. 2018 A Thioredoxin domain-containing pirotein Interacts with pepino mosaic virus triple gene block protein 1. International Journal of Molecular Science , 19, e3747.
Kavroulakis, N., Doupis, G., Papadakis, I.E., Ehaliotis, C., Papadopoulou, K.K. 2018 Tolerance of tomato plants to water stress is improved by the root endophyte Fusarium solani FsK Rhizosphere, 6, 77-85.
Mathioudakis, M. M. and Livieratos I. 2015 A pharmacological approach for silencing Hsp70 by application of quercetin in Nicotiana benthamiana plants to study the effect on plant virus infection. Bio-protocol , 5, e1675.
Owen, C., Mathioudakis, M.M., Gazivoda, A., Gal, P., Nol, N., Kalliampakou, K., Figas, A., Bellan, A., Iparaguirre, A., Rubio, L., Livieratos, I. 2014 Evolution and molecular epidemiology of citrus tristeza virus on Crete. Journal of Phytopathology , 162, 839-843.
Mathioudakis, M.M., Rodríguez-Moreno, R., Sempere, R.N., Aranda, M.A., Livieratos, I. 2014 Multifaceted capsid proteins: Multiple interactions suggest multiple roles for pepino mosaic virus capsid protein. Molecular Plant-Microbe Interactions , 27, 1356-1359.
Mathioudakis, M.M., Veiga, R.S.L., Canto, T., Medina, V., Mossialos, D., Makris, A.M., Livieratos, I. 2013 Pepino mosaic virus triple gene block protein 1 (TGBp1) interacts with and increases tomato catalase 1 activity to enhance virus accumulation. Molecular Plant Pathology , 14, 589-601.
Mathioudakis, M.M., Candresse, T., Barone, M., Rogozzino, A., Katis, N.I. 2012 Cydonia japonica, Pyrus calleryana and P. amygdaliformis: three new ornamental or wild hosts of apple stem pitting virus. Virus Genes , 44, 319-322.
Mathioudakis, M.M., Veiga, R., Ghita, M., Tsikou, D., Medina, V., Canto, T., Makris, A.M., Livieratos, I.C. 2012 Pepino mosaic virus capsid protein interacts with a tomato heat shock protein cognate 70. Virus Research , 163, 28-39.
Mathioudakis, M.M., Maliogka, V.I., Katsiani, A.T., Katis N.I. 2010 Incidence and molecular variability of apple stem pitting and apple chlorotic leaf spot viruses in apple and pear orchards in Greece Journal of Plant Pathology , 92, 141-149.
Mathioudakis, M.M., Maliogka, V.I., Dovas , C.I., Paunovic, S., Katis, N.I. 2009 Reliable RT-PCR detection of apple stem pitting virus in pome fruits and its association with quince fruit deformation disease. Plant Pathology , 58, 228-236.
Mathioudakis, M.M., Candresse, T., Katis, N.I. 2007 First report of apple chlorotic leaf spot virus (ACLSV) in quince in Greece. Plant Disease , 91, 462.
Mathioudakis, M.M., Maliogka, V.I., Dovas , C.I., Vasilakakis, M., Katis, N.I. 2006 First record of the apple stem pitting virus (ASPV) in quince in Greece. Journal of Plant Pathology , 88, 225.